Coagulants are chemicals that facilitate the aggregation of suspended particles in wastewater, allowing them to form larger particles or flocs. Common coagulants include aluminum sulfate (alum) and ferric chloride, which neutralize the negative charges on particles, promoting their aggregation. Following coagulation, flocculants — such as polyacrylamide — enhance the formation and settling of these flocs in the sedimentation process. This step is crucial in removing solids and turbidity from sewage, making it a fundamental part of primary treatment.
Finally, the handbook encourages continued research and innovation in the field of plastic and polymer additives. As new materials and technologies emerge, the ongoing evolution of analytical methods will be essential to keep pace. Collaborative efforts between academia, industry, and regulatory bodies will contribute to the development of safer, more effective additives and enhance our understanding of their environmental and health impacts.
Quality control (QC) and quality assurance (QA) are fundamental components of the API manufacturing process. All steps of manufacturing must meet stringent regulatory requirements set by authorities such as the FDA or EMA. QC involves rigorous testing of raw materials and the intermediate and final products to ensure they meet predefined standards. These tests often include chemical analysis, microbiological testing, and stability studies. QA, on the other hand, encompasses the overall system of procedures and protocols that ensure consistent production quality, including documentation practices, employee training, and validation of equipment.